Steroids and derivatives
Medchemexpress LLC Estra-1,3,5(10)-triene-3,17-diol (17β)-, 17-(hydrogen butanedioate) | 7698-93-3 | 98.8% | 372.45 | 100 MG
β-Estradiol 17-hemisuccinate is a synthetic derivative of estradiol. This compound is a white to off-white solid with a purity of 98.8%. It is suitable for research applications.
- Synthetic derivative of estradiol
- Purity of 98.8%
- Molecular weight of 372.45
- White to off-white solid appearance
- Store at 4°C under nitrogen
- Store in solvent at -80°C for 6 months or -20°C for 1 month
- Soluble in DMSO
Medchemexpress LLC Estra-1,3,5(10)-triene-3,17-diol (17β)-, 17-(hydrogen butanedioate) | 7698-93-3 | 98.8% | 372.45 | 50 MG
β-Estradiol 17-hemisuccinate is a synthetic derivative of estradiol, appearing as a white to off-white solid.
- Synthetic derivative of estradiol.
- CAS number: 7698-93-3.
- Molecular weight: 372.45.
- Chemical formula: C22H28O5.
- Purity: 98.8%.
- Store at 4°C, stored under nitrogen.
- Store in solvent at -80°C for 6 months or -20°C for 1 month, stored under nitrogen.
- 1H NMR spectrum and LCMS consistent with structure.
Medchemexpress LLC Estra-1,3,5(10)-triene-2,4,16,16-d4-3,17-diol, 3-(hydrogen sulfate), sodium salt, (17a)- | 352431-50-6 | 99.6% | 378.45 g/mol | C18H19D4NaO5S | 5 MG
17β-Estradiol sulfate-d4 (sodium) is a deuterium-labeled sodium salt of 17β-estradiol 3-sulfate supplied as a high-purity analytical standard for research use. It is intended as an internal standard or tracer in mass spectrometry and other quantitative assays to study estradiol metabolism and sulfate conjugates.
- Deuterium-labeled (d4) analog for isotope dilution and tracer studies.
- Sodium salt supplied as a solid, suitable for long-term storage.
- High purity (~99.6%) for analytical applications.
- Molecular formula C18H19D4NaO5S; molecular weight 378.45 g/mol.
- For research use only; not for human or clinical use.
Cayman Chemical Ethynyl Estradiol
An estrogen receptor agonist (EC50 = 8.5 pM in a reporter assay using T47D cells); reduces serum cholesterol levels and femur bone mass and increases uterine mass in an OVX rat model of postmenopause at 0.1 mg/kg per day; has been found in wastewater effluent; prevents secondary sexual development in male fathead minnows and increases the numbers of intersex fish at 4 ng/l
Medchemexpress LLC Estradiol cypionate | 313-06-4 | MFCD00056558 | 99.5% | 1 ML
Estradiol cypionate is the 17β-cypionate ester of Estradiol, inhibiting ET-1 synthesis by acting on estrogen receptors. It is intended for research use only. In vitro, it inhibits proliferation of gastric cancer cells and induces G1/S phase cell cycle arrest and apoptosis by affecting the PI3K/Akt/mTOR pathway. In vivo, it increases cortical bone density in ovariectomized rabbits, increases occurrence of estrus and pregnancy in cows, and inhibits tumor growth in MGC803 nude mice tumor models.
- Inhibits gastric cancer cell proliferation
- Induces G1/S phase cell cycle arrest and apoptosis
- Increases cortical bone density
- Promotes estrus and pregnancy
- Inhibits tumor growth
Apexbio Technology LLC α-Estradiol 57-91-0 10mM (in 1mL Ethanol)
alpha-Estradiol (57-91-0) is a small-molecule inhibitor targeting 5 -reductase the enzyme responsible for converting testosterone to dihydrotestosterone (DHT) It is designed to inhibit 5 -reductase activity thereby modulating androgen metabolism and androgen-related signaling pathways alpha-Estradiol exerts its biological activity primarily through enzyme inhibition In reported experimental studies alpha-Estradiol demonstrates inhibitory activity against 5 -reductase with an IC50 value ranging from approximately 1 to 10 M though the precise value may depend on assay conditions Based on these pharmacological properties alpha-Estradiol holds research potential in the treatment and study of androgenetic alopecia
Medchemexpress LLC Alpha-estradiol | 57-91-0 | MFCD00064144 | 99.9% | 272.39 | C18H24O2 | 10 MG
Alpha-estradiol (analytical standard) is a reference material intended for analytical testing and method development. It is a weak estrogen and a 5α-reductase inhibitor supplied as a high-purity solid suitable for calibration, qualitative analyses, and quantitative assays in research and laboratory workflows.
- Analytical reference standard for research and method validation.
- High stated purity for accurate calibration (99.93%).
- Supplied as a solid for convenient handling and storage.
- Available in small pack sizes appropriate for analytical use (10 mg).
- Applicable to studies of estrogenic activity and 5α-reductase inhibition.
Cambridge Isotope Laboratories Estradiol (unlabeled) 100 ug/mL in acetonitrile 1 2 mL
Estradiol (unlabeled) 100 ug/mL in acetonitrile 1 2 mL
Medchemexpress LLC β-estradiol-6-CMO-PEG3-biotin | 2938875-38-6 | 97.8% | 759.95 g·mol⁻¹ | C38H57N5O9S | 1 MG
β-Estradiol-6-CMO-PEG3-biotin is a biotinylated estradiol derivative used as a cleavable three-unit polyethylene glycol (PEG3) linker for antibody-drug conjugate (ADC) synthesis. It provides a hydrophilic spacer and a biotin handle to facilitate conjugation, affinity capture, and detection in downstream assays.
- Cleavable three-unit PEG linker providing hydrophilicity and spacing.
- Biotin tag enables affinity capture and detection.
- High purity (97.82%) suitable for research applications.
- Soluble in DMSO at ≥ 50 mg/mL; use freshly opened DMSO.
- Stable as a powder at -20°C for up to 3 years; limited stability in solvent as specified by manufacturer.
Cayman Chemical 2-bromo 17-EstradIol 25mg
A synthetic steroid and inhibitor of estrogen 2-hydroxylase; inhibits estrogen 2-hydroxylase in rat liver microsomes at 50 and 100 µM; prevents estrogen-induced inhibition of apomorphine-induced climbing behavior in mice at 5 mg/kg
Medchemexpress LLC Estra-1,3,5(10)-triene-3,17-diol (17β)-, 3-sulfamate | 172377-52-5 | MFCD00947822 | 351.46 | 25 MG
Estradiol 3-sulfamate, also identified as BLE 00084, E2MATE, or ES-J 995, is characterized as a potent, long-acting, and orally active inhibitor of steroid sulfatase.
- Potent steroid sulfatase inhibitor
- Long-acting steroid sulfatase inhibitor
- Orally active steroid sulfatase inhibitor
- Inhibits estrone sulfatase with an IC50 of 251 nM
- Inhibits estrone sulfatase with a Ki of 133 nM
Sigma Aldrich Fine Chemicals Biosciences beta-Estradiol 17-beta-D-g10MG
BETA7 beta-Estradiol 17-beta-D-g10MG
Cayman Chemical Ethynyl Estradiol
An estrogen receptor agonist (EC50 = 8.5 pM in a reporter assay using T47D cells); reduces serum cholesterol levels and femur bone mass and increases uterine mass in an OVX rat model of postmenopause at 0.1 mg/kg per day; has been found in wastewater effluent; prevents secondary sexual development in male fathead minnows and increases the numbers of intersex fish at 4 ng/l
Cayman Chemical 17-EstradIol-d3 1mg
An internal standard for the quantification of 17β-estradiol by GC- or LC-MS
Cayman Chemical 17-EstradIol-d3 5mg
An internal standard for the quantification of 17β-estradiol by GC- or LC-MS